Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 6/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420341 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ETDP1LMNA | |
| SCHEMBL8207302 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4ETDP1PTGDR2 | |
| SCHEMBL8420212 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ETDP1LMNA | |
| SCHEMBL693383 | 0.74 | TDP1 (0.49) | ALDH1A1HPGDKDM4ETDP1PTGIR | |
| Naphthyloxyacetic Acid SCHEMBL6820182 | 0.68 | KDM4E (0.96) | ALDH1A1HPGDKDM4ETDP1PTGDR2 | |
| SCHEMBL18065062 | 0.68 | TDP1 (0.71) | ALDH1A1TDP1LMNAHTTNPSR1 | |
| SCHEMBL28692953 | 0.68 | TDP1 (0.71) | ALDH1A1TDP1LMNAHTTNPSR1 | |
| SCHEMBL7294511 | 0.68 | PTGDR2 (0.61) | ALDH1A1HPGDKDM4EPTGDR2LMNA | |
| SCHEMBL2649228 | 0.68 | PTGDR2 (0.66) | ALDH1A1HPGDKDM4ETDP1PTGDR2 | |
| SCHEMBL8202557 | 0.68 | SLC6A9 (0.48) | ALDH1A1HPGDKDM4ETDP1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | claimed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |