Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.43 |
| ▸ | PTGIR | P43119 | 5/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420341 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL8420212 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL13497110 | 0.79 | CNR2 (0.44) | TSHRTACR3KMT2AMEN1TAAR1 | |
| SCHEMBL693383 | 0.78 | TDP1 (0.49) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL6563571 | 0.77 | KDM4E (0.65) | ALDH1A1HPGDKDM4ETDP1PARP1 | |
| SCHEMBL8416828 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| Naphthyloxyacetic Acid SCHEMBL6820182 | 0.73 | KDM4E (0.96) | ALDH1A1HPGDKDM4ETDP1TSHR | |
| SCHEMBL22340596 | 0.72 | ALDH1A1 (0.75) | ALDH1A1HPGDSMN1; SMN2GLAL3MBTL1 | |
| SCHEMBL8202557 | 0.72 | SLC6A9 (0.48) | ALDH1A1HPGDKDM4ETDP1POLB | |
| SCHEMBL901768 | 0.72 | TDP1 (0.47) | ALDH1A1HPGDKDM4ETDP1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | claimed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |
| US-6013673-A | ADMINISTERING AN EFFECTIVE AMOUNT OF A NAPHTHYLOXYACETIC ACID DERIVATIVE OR NONTOXIC ACID ADDITION SALT OR HYDRATE TO TREAT OR PREVENT ABORTION, PAINE, DIARRHEA, CATHARTICS, ULCER, GASTRITIS, HYPERTENSION AND THROMBOSIS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-11 | — | — | US | disclosed |
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | disclosed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |