Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418748 | 1.00 | KMT2A (0.53) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL693383 | 0.89 | TDP1 (0.49) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL8202557 | 0.81 | SLC6A9 (0.48) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL8202181 | 0.81 | TSHR (0.48) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL8202190 | 0.81 | MAPK1 (0.43) | KMT2AMEN1POLBMAPTMAPK1 | |
| SCHEMBL8206250 | 0.80 | MAPT (0.47) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL8420406 | 0.79 | KDM4E (0.51) | KMT2AMEN1MAPTMAPK1HTT | |
| SCHEMBL901768 | 0.78 | TDP1 (0.47) | POLBMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL8420212 | 0.77 | ALDH1A1 (0.51) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL8201916 | 0.77 | KMT2A (0.52) | KMT2AMEN1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | claimed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |