Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.38 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.38 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | IRS1 | P35568 | 1/20 | 0.36 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417532 | 0.93 | SIGMAR1 (0.40) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8419633 | 0.91 | SIGMAR1 (0.39) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8419845 | 0.90 | SIGMAR1 (0.40) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8418072 | 0.87 | SIGMAR1 (0.39) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8417294 | 0.87 | LMNA (0.45) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8417445 | 0.86 | SIGMAR1 (0.40) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8418158 | 0.85 | LMNA (0.43) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8417431 | 0.85 | EEF2K (0.37) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8419365 | 0.84 | SIGMAR1 (0.40) | FFAR1FFAR4SIGMAR1ALDH1A1ATM | |
| SCHEMBL8417302 | 0.84 | ALDH1A1 (0.46) | ALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |