Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 14/20 | 0.37 |
| ▸ | MMP2 | P08253 | 4/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8418615 | 0.97 | FDFT1 (0.37) | FDFT1MMP13MMP2GPR119 | |
| SCHEMBL8968385 | 0.88 | MMP13 (0.39) | FDFT1MMP13MMP2 | |
| SCHEMBL8772717 | 0.87 | SIGMAR1 (0.43) | MMP13 | |
| SCHEMBL8969873 | 0.86 | MMP13 (0.40) | FDFT1MMP13MMP2 | |
| Hydrochloric Acid SCHEMBL8772629 | 0.84 | SIGMAR1 (0.43) | MMP13 | |
| SCHEMBL27458909 | 0.83 | MMP13 (0.38) | FDFT1MMP13MMP2 | |
| SCHEMBL8969019 | 0.81 | LTA4H (0.42) | FDFT1MMP13MMP2 | |
| Hydrochloric Acid SCHEMBL8968667 | 0.79 | LTA4H (0.42) | FDFT1MMP13MMP2 | |
| SCHEMBL8968633 | 0.78 | CHRM2 (0.39) | FDFT1MMP13MMP2 | |
| SCHEMBL8706049 | 0.77 | MMP13 (0.36) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |