Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PRNP | P04156 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418203 | 0.84 | HPGD (0.66) | POLBTDP1RXFP1LMNARECQL | |
| SCHEMBL10654575 | 0.83 | TDP1 (0.79) | POLBTDP1RXFP1LMNARECQL | |
| SCHEMBL2223391 | 0.76 | ALDH1A1 (0.59) | POLBTDP1RXFP1LMNARECQL | |
| SCHEMBL13838138 | 0.75 | LMNA (0.88) | POLBTDP1RXFP1LMNARECQL | |
| SCHEMBL432295 | 0.72 | RXFP1 (0.62) | POLBTDP1RXFP1LMNARECQL | |
| SCHEMBL2315352 | 0.72 | LMNA (0.61) | POLBTDP1RXFP1LMNARECQL | |
| SCHEMBL8421487 | 0.72 | HDAC3 (0.57) | TDP1RXFP1LMNAHDAC3HDAC4 | |
| SCHEMBL25616720 | 0.71 | POLB (0.66) | POLBTDP1RXFP1LMNARECQL | |
| SCHEMBL14190598 | 0.71 | MAPT (0.50) | POLBTDP1RXFP1LMNARECQL | |
| SCHEMBL14190930 | 0.71 | HPGD (0.53) | POLBTDP1RXFP1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |