Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417361 | 0.95 | DAGLA (0.34) | DAGLANPSR1LMNAAGTR1AGTR2 | |
| SCHEMBL7202719 | 0.85 | DAGLA (0.35) | DAGLANPSR1LMNAAGTR1AGTR2 | |
| SCHEMBL838908 | 0.85 | SLC9A1 (0.36) | DAGLANPSR1LMNAAGTR1AGTR2 | |
| SCHEMBL5357964 | 0.84 | LMNA (0.35) | NPSR1LMNAAGTR1AGTR2HSD11B1 | |
| SCHEMBL3568399 | 0.84 | SLC9A1 (0.35) | DAGLANPSR1LMNAAGTR1AGTR2 | |
| SCHEMBL14032263 | 0.81 | AGTR1 (0.35) | DAGLANPSR1LMNAAGTR1AGTR2 | |
| SCHEMBL3260686 | 0.81 | CYP2A6 (0.34) | NPSR1LMNAAGTR1AGTR2HSD11B1 | |
| SCHEMBL22615880 | 0.81 | HSD11B1 (0.36) | DAGLANPSR1LMNAAGTR1AGTR2 | |
| SCHEMBL2970884 | 0.80 | LMNA (0.36) | DAGLANPSR1LMNAHTTALDH1A1 | |
| SCHEMBL2359649 | 0.78 | LMNA (0.35) | NPSR1LMNAAGTR1AGTR2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684257-B1 | Pseudopeptide derivatives of neurokinines, process for their preparation and pharmaceutical compositions comprising them | ADIR (FR) | 1999-09-22 | — | — | EP | disclosed |
| US-5561113-A | ANALGESICS; ANTIIFLAMMATORY AGENTS; GASTROINTESTINAL, UROGENITAL AND NERVOUS SYSTEM(CNS) DISORDERS; ASTHMA; ANTIALLERGENS | ADIR ET COMPAGNIE (FR) | 1996-10-01 | — | — | US | disclosed |
| EP-0684257-A1 | Pseudopeptide derivatives of neurokinines, process for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1995-11-29 | — | — | EP | disclosed |