Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421884 | 0.85 | KDM4E (0.34) | PDGFRB | |
| SCHEMBL8422031 | 0.83 | FDPS (0.33) | PDGFRBKMT2A | |
| SCHEMBL8421763 | 0.83 | EGFR (0.34) | KMT2A | |
| SCHEMBL8417915 | 0.79 | ACACB (0.37) | KMT2A | |
| SCHEMBL8919898 | 0.78 | MYC (0.37) | TSHRJAK1JAK3POLBMAPT | |
| SCHEMBL8421925 | 0.73 | FFAR1 (0.34) | L3MBTL1KMT2A | |
| SCHEMBL9431924 | 0.73 | MMP13 (0.52) | — | |
| SCHEMBL8919982 | 0.71 | MMP13 (0.46) | POLBNPC1 | |
| SCHEMBL8420487 | 0.70 | TSHR (0.31) | TSHR | |
| SCHEMBL8969537 | 0.69 | MMP13 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |