Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918241 | 0.86 | SPHK1 (0.45) | CHRM5CHRM1CHRM3LMNASPHK1 | |
| SCHEMBL8417998 | 0.79 | FDFT1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL8421884 | 0.76 | KDM4E (0.34) | KCNH2KDM4E | |
| SCHEMBL8921096 | 0.74 | ALDH1A1 (0.35) | HRH3ALDH1A1L3MBTL3L3MBTL1CHRNA7 | |
| SCHEMBL8420023 | 0.73 | TSHR (0.35) | KMT2AL3MBTL1 | |
| SCHEMBL8707234 | 0.71 | HRH3 (0.37) | HRH3ACACBKDM4E | |
| SCHEMBL8920052 | 0.71 | KMT2A (0.53) | LMNAALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL8420280 | 0.68 | HRH3 (0.33) | FFAR4HRH3CYP2D6 | |
| SCHEMBL8420501 | 0.67 | MEN1 (0.39) | HRH3KCNH2ALDH1A1MEN1CYP2D6 | |
| SCHEMBL8969941 | 0.67 | FDFT1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |