Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365195 | 0.79 | CHRM2 (0.39) | HTTLMNAKMT2ACHRM2CHRM1 | |
| Cadaverine Tartrate SCHEMBL8420068 | 0.77 | HTT (0.38) | HTTLMNAKMT2AHSD11B1CHRM2 | |
| SCHEMBL7567319 | 0.75 | CHRM2 (0.39) | HTTLMNAKMT2ACHRM2CHRM1 | |
| SCHEMBL7618980 | 0.72 | ALDH1A1 (0.42) | HTTLMNAKMT2AHSD11B1CHRM2 | |
| SCHEMBL4607776 | 0.72 | LMNA (0.32) | LMNATSHR | |
| SCHEMBL15619381 | 0.70 | LMNA (0.31) | HTTLMNAKMT2A | |
| Lactic Acid SCHEMBL6365192 | 0.70 | CHRM2 (0.40) | HTTLMNAKMT2ACHRM2CHRM1 | |
| SCHEMBL2987446 | 0.68 | ALDH1A1 (0.38) | HTTLMNAKMT2AHSD11B1CHRM2 | |
| Bicarbonate SCHEMBL5227 | 0.68 | ALDH1A1 (0.41) | HTTLMNAKMT2AHSD11B1CHRM2 | |
| SCHEMBL7566192 | 0.67 | ALDH1A1 (0.39) | HTTLMNAKMT2AHSD11B1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941065-A1 | IONOPHORE-MEDIATED LIPOSOME LOADING OF WEAKLY BASIC DRUG | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1999-09-15 | — | — | EP | disclosed |
| US-5837282-A | DRUG DELIVERY; ENCAPSULATION OF A WEAKLY BASIC DRUG | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1998-11-17 | — | — | US | disclosed |
| WO-1998018450-A1 | IONOPHORE-MEDIATED LIPOSOME LOADING OF WEAKLY BASIC DRUG | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1998-05-07 | — | — | WO | disclosed |