Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419007 | 0.90 | HTT (0.45) | HTTSMN1; SMN2POLBNR1H4ITGB3 | |
| SCHEMBL8418917 | 0.89 | POLB (0.47) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8768556 | 0.88 | ALDH1A1 (0.45) | POLBLTA4H | |
| SCHEMBL8420680 | 0.81 | NR1H4 (0.39) | HTTSMN1; SMN2POLBNR1H4 | |
| SCHEMBL8422577 | 0.79 | HTT (0.54) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8768504 | 0.77 | ALDH1A1 (0.46) | HTTSMN1; SMN2POLBLTA4H | |
| SCHEMBL8418610 | 0.77 | HTT (0.51) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8420643 | 0.76 | POLB (0.51) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8767951 | 0.76 | HTT (0.53) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8422541 | 0.76 | POLB (0.48) | HTTSMN1; SMN2POLBNR1H4LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | claimed |
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |