Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420681 | 0.90 | HTT (0.44) | HTTSMN1; SMN2POLBNR1H4ITGB3 | |
| SCHEMBL8418917 | 0.88 | POLB (0.47) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8768504 | 0.87 | ALDH1A1 (0.46) | HTTSMN1; SMN2POLBLTA4HGAA | |
| SCHEMBL8422577 | 0.81 | HTT (0.54) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8418610 | 0.78 | HTT (0.51) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8420643 | 0.78 | POLB (0.51) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8767951 | 0.78 | HTT (0.53) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8768556 | 0.77 | ALDH1A1 (0.45) | POLBLTA4HHPGD | |
| SCHEMBL8422541 | 0.77 | POLB (0.48) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8767987 | 0.77 | HTT (0.49) | HTTSMN1; SMN2POLBNR1H4LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |