Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | BRD1 | O95696 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686126 | 0.84 | HIF1A (0.45) | PKMTRIM24BRD1BRPF1HIF1A | |
| SCHEMBL9333621 | 0.81 | HIF1A (0.33) | PKMTRIM24BRD1BRPF1HIF1A | |
| SCHEMBL30511906 | 0.76 | PKM (0.58) | PKMTRIM24BRD1BRPF1PKLR | |
| SCHEMBL639690 | 0.76 | PKM (0.58) | PKMTRIM24BRD1BRPF1PKLR | |
| SCHEMBL433187 | 0.72 | MAPT (0.45) | HIF1AEPAS1 | |
| SCHEMBL4417328 | 0.72 | BACE1 (0.37) | HTT | |
| SCHEMBL23536157 | 0.72 | OGA (0.41) | PKMHIF1AEPAS1PKLR | |
| SCHEMBL1506790 | 0.71 | RXRA (0.50) | — | |
| SCHEMBL9737788 | 0.70 | — | — | |
| SCHEMBL10689616 | 0.69 | CA2 (0.45) | PKMHIF1AEPAS1PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948480-A1 | SULPHONYL COMPOUNDS FOR USE AS LINKERS IN SOLID PHASE AND COMBINATORIAL SYNTHESIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998029386-A1 | SULPHONYL COMPOUNDS FOR USE AS LINKERS IN SOLID PHASE AND COMBINATORIAL SYNTHESIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-09 | — | — | WO | disclosed |