Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | WRN | Q14191 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2618716 | 0.92 | ALDH1A1 (0.63) | ALDH1A1DGKACES2CES1DNM1 | |
| Bis(Butyryloxymethyl) Succinate SCHEMBL18747588 | 0.89 | ALDH1A1 (0.60) | ALDH1A1DGKACES2CES1DNM1 | |
| Ethyl Propionate SCHEMBL28240255 | 0.87 | ALDH1A1 (0.59) | ALDH1A1NAAADGKACES2CES1 | |
| SCHEMBL181440 | 0.87 | ALDH1A1 (0.59) | ALDH1A1NAAADGKACES2CES1 | |
| SCHEMBL681192 | 0.86 | NAAA (0.52) | ALDH1A1NAAAFFAR3CYP1A2HPGD | |
| SCHEMBL7645974 | 0.84 | ALDH1A1 (0.55) | ALDH1A1DGKACES2CES1DNM1 | |
| SCHEMBL3831118 | 0.84 | DGKA (0.54) | ALDH1A1NAAADGKADNM1PAM | |
| Methane SCHEMBL6300031 | 0.83 | NAAA (0.50) | ALDH1A1NAAADGKAFFAR3CYP1A2 | |
| SCHEMBL3839547 | 0.82 | ALDH1A1 (0.52) | ALDH1A1DGKACES2CES1FFAR3 | |
| SCHEMBL3831128 | 0.82 | DGKA (0.64) | ALDH1A1DGKADNM1PAMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469728-B2 | Temperature and pH-sensitive block copolymer having excellent safty in vivo and hydrogel and drug delivery system using thereof | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE (KR) | 2016-10-18 | — | — | US | disclosed |
| US-7902268-B2 | Water soluble energy curable stereo-crosslinkable ionomer compositions | SUN CHEMICAL CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| US-7696226-B2 | HIV protease inhibiting compounds | ABBOTT LABORATORIES (US) | 2010-04-13 | — | — | US | disclosed |
| US-7300992-B2 | Vinyl polymers and processes for producing the same | KANEKA CORPORATION (JP) | 2007-11-27 | — | — | US | disclosed |
| US-20050159469-A1 | HIV protease inhibiting compounds | ABBVIE INC. | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159469-A1 | HIV protease inhibiting compounds | SERPINB1, HPN, DNPEP | ALDH1A1 2920/4885NAAA 516/4885DGKA 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.