Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.50 |
| ▸ | MMP9 | P14780 | 8/20 | 0.50 |
| ▸ | MMP3 | P08254 | 7/20 | 0.50 |
| ▸ | MMP1 | P03956 | 6/20 | 0.50 |
| ▸ | MMP14 | P50281 | 6/20 | 0.50 |
| ▸ | MMP8 | P22894 | 4/20 | 0.50 |
| ▸ | MMP7 | P09237 | 4/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 5/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | AOC2 | O75106 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423697 | 0.91 | MMP2 (0.43) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL8423692 | 0.86 | MMP2 (0.39) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL8428006 | 0.85 | MMP2 (0.39) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL8426091 | 0.80 | MMP2 (0.47) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL4292169 | 0.78 | MMP2 (0.67) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL27530823 | 0.78 | MMP1 (0.44) | MMP2MMP9MMP3MMP1MMP14 | |
| Hydrochloric Acid SCHEMBL8425471 | 0.78 | MMP1 (0.48) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL12020262 | 0.74 | MMP2 (0.69) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL6796941 | 0.69 | MMP3 (0.56) | MMP2MMP9MMP3MMP1MMP14 | |
| SCHEMBL8423721 | 0.69 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |