Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.44 |
| ▸ | MMP2 | P08253 | 9/20 | 0.44 |
| ▸ | MMP9 | P14780 | 8/20 | 0.44 |
| ▸ | MMP14 | P50281 | 5/20 | 0.44 |
| ▸ | MMP13 | P45452 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | MMP7 | P09237 | 4/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | MMP10 | P09238 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AOC2 | O75106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426091 | 0.85 | MMP2 (0.47) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL8425302 | 0.78 | MMP2 (0.50) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL8423697 | 0.76 | MMP2 (0.43) | MMP1MMP2MMP9MMP14MMP3 | |
| Hydrochloric Acid SCHEMBL8425471 | 0.72 | MMP1 (0.48) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL8428006 | 0.71 | MMP2 (0.39) | MMP1MMP2MMP9MMP14MMP3 | |
| SCHEMBL4421598 | 0.71 | CCR2 (0.50) | KMT2AMEN1LMNA | |
| SCHEMBL4421591 | 0.71 | CCR2 (0.50) | KMT2AMEN1LMNA | |
| SCHEMBL8423692 | 0.70 | MMP2 (0.39) | MMP1MMP2MMP9MMP14MMP3 | |
| SCHEMBL17026726 | 0.68 | MMP2 (0.58) | MMP1MMP2MMP9MMP14MMP3 | |
| SCHEMBL11483420 | 0.67 | MMP1 (0.51) | MMP1MMP2HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240208-A | Process for preparing 3-arylsulfur hydroxamic acids | HOFFMANN LA ROCHE (CH) | 2000-01-05 | — | — | CN | disclosed |