Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 9/20 | 0.50 |
| ▸ | MMP9 | P14780 | 8/20 | 0.50 |
| ▸ | MMP13 | P45452 | 8/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 8/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428232 | 0.92 | MMP9 (0.45) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL8428183 | 0.79 | MMP1 (0.53) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL27477097 | 0.77 | MMP1 (0.47) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7302817 | 0.77 | MMP1 (0.67) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7301752 | 0.76 | MMP1 (0.52) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7303679 | 0.73 | MMP13 (0.67) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL8425264 | 0.70 | MMP1 (0.44) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7310514 | 0.69 | MMP1 (0.49) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL5919626 | 0.69 | MMP9 (0.67) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL7405390 | 0.69 | MMP13 (0.78) | MMP1MMP9MMP13ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |