Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.44 |
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428183 | 0.82 | MMP1 (0.53) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL8428232 | 0.79 | MMP9 (0.45) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL7308211 | 0.71 | MMP1 (0.76) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL8425323 | 0.70 | MMP1 (0.50) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL16087984 | 0.68 | MMP13 (0.58) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL4294133 | 0.67 | LMNA (0.50) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL8425462 | 0.64 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL4294130 | 0.64 | LMNA (0.50) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL15625452 | 0.62 | BCL2L1 (0.62) | MMP1MMP13MMP9MMP2MMP3 | |
| Diphenylether SCHEMBL1830446 | 0.62 | LTA4H (0.67) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |