Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.45 |
| ▸ | MMP2 | P08253 | 4/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 8/20 | 0.43 |
| ▸ | MMP13 | P45452 | 7/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425323 | 0.92 | MMP1 (0.50) | MMP9MMP2MMP1MMP13ADAM17 | |
| SCHEMBL8428183 | 0.88 | MMP1 (0.53) | MMP9MMP2MMP1MMP13ADAM17 | |
| SCHEMBL8425264 | 0.79 | MMP1 (0.44) | MMP9MMP2MMP1MMP13ADAM17 | |
| SCHEMBL7310514 | 0.78 | MMP1 (0.49) | MMP9MMP2KDM2BMMP1MMP13 | |
| SCHEMBL5919626 | 0.78 | MMP9 (0.67) | MMP9MMP2MMP1MMP13ADAM17 | |
| Hydrochloric Acid SCHEMBL6537429 | 0.77 | MMP9 (0.66) | MMP9MMP2MMP1MMP13ADAM17 | |
| SCHEMBL7299271 | 0.76 | MMP1 (0.66) | MMP9MMP2KDM2BMMP1MMP13 | |
| SCHEMBL7308944 | 0.74 | MMP1 (0.51) | MMP9MMP2KDM2BMMP1MMP13 | |
| SCHEMBL8428266 | 0.71 | HTR2A (0.53) | MMP9MMP2KDM2BMMP1MMP13 | |
| SCHEMBL8428264 | 0.70 | MMP2 (0.48) | MMP9MMP2KDM2BMMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |