Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427548 | 1.00 | CCR5 (0.32) | CCR5PYGL | |
| SCHEMBL8426463 | 0.81 | DPP4 (0.36) | PYGL | |
| SCHEMBL965716 | 0.80 | CCR5 (0.39) | CCR5 | |
| SCHEMBL969305 | 0.78 | L3MBTL1 (0.41) | CCR5 | |
| SCHEMBL970246 | 0.77 | L3MBTL1 (0.44) | CCR5 | |
| SCHEMBL968899 | 0.75 | L3MBTL1 (0.46) | — | |
| SCHEMBL8239143 | 0.73 | — | — | |
| SCHEMBL8248970 | 0.73 | — | — | |
| SCHEMBL9008706 | 0.72 | SLC6A4 (0.39) | CCR5 | |
| SCHEMBL20414687 | 0.71 | CCR5 (0.32) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446114-B2 | Quinolinone compounds as 5-HT4 receptor agonists | THERAVANCE, INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-20060199839-A1 | Quinolinone compounds as 5-HT4 receptor agonists | THERAVANCE, INC. | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199839-A1 | Quinolinone compounds as 5-HT4 receptor agonists | HTR4, HTR5A, HTR1A | CCR5 292/4885PYGL 3520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.