Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.60 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13115728 | 0.83 | TSHR (0.69) | HPGDTSHRRAB9AMEN1KMT2A | |
| SCHEMBL4936220 | 0.83 | RAB9A (0.63) | HPGDTSHRRAB9AMEN1KMT2A | |
| SCHEMBL12376672 | 0.82 | HPGD (0.59) | HPGDTSHRRAB9AMEN1KMT2A | |
| SCHEMBL8247489 | 0.82 | KMT2A (0.74) | HPGDTSHRRAB9AMEN1KMT2A | |
| SCHEMBL15332743 | 0.82 | PKM (0.49) | HPGDTSHRRAB9AMEN1KMT2A | |
| SCHEMBL13209141 | 0.81 | ALDH1A1 (0.72) | TSHRRAB9AMEN1KMT2APOLB | |
| SCHEMBL5000478 | 0.81 | LMNA (0.62) | HPGDTSHRRAB9AMEN1KMT2A | |
| SCHEMBL5523413 | 0.80 | KMT2A (0.57) | HPGDTSHRRAB9AMEN1KMT2A | |
| SCHEMBL24112746 | 0.80 | TDP1 (0.72) | HPGDTSHRRAB9AMEN1KMT2A | |
| SCHEMBL12017484 | 0.79 | LMNA (0.51) | HPGDTSHRRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504431-B2 | Sulfonyl amide inhibitors of calcium channel function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-03-17 | — | — | US | disclosed |
| US-20050245535-A1 | Sulfonyl amide inhibitors of calcium channel function | BRISTOL- MYERS SQUIBB COMPANY | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245535-A1 | Sulfonyl amide inhibitors of calcium channel function | CACNA1F, CACNA1A, CACNA1D | HPGD 3069/4885TSHR 1902/4885RAB9A 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.