Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428702 | 0.72 | CTH (0.42) | SLC6A3CYP19A1ALDH1A1MAPTKDM4E | |
| SCHEMBL8428699 | 0.72 | CTH (0.42) | SLC6A3CYP19A1ALDH1A1MAPTKDM4E | |
| SCHEMBL8426401 | 0.70 | TRPA1 (0.50) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL8426400 | 0.70 | TRPA1 (0.50) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL19076193 | 0.70 | CYP1A2 (0.56) | CYP19A1CYP11B2ALDH1A1MAPTKDM4E | |
| SCHEMBL8428337 | 0.69 | TP53 (0.47) | ALDH1A1MAPTGAAHTTTSHR | |
| SCHEMBL28461031 | 0.68 | — | — | |
| SCHEMBL16478537 | 0.68 | RAB9A (0.45) | ALDH1A1MAPTKDM4ELMNAGAA | |
| SCHEMBL7592948 | 0.67 | TRPA1 (0.50) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL7592950 | 0.67 | TRPA1 (0.50) | ALDH1A1MAPTKDM4EGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939561-A | Process for the preparation of β-phenylisoserine and β-lactam and their analogues | RHONE-POULENCE RORER S.A. (FR) | 1999-08-17 | — | — | US | disclosed |