Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428699 | 1.00 | CTH (0.42) | CTHMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL16478537 | 0.76 | RAB9A (0.45) | CTHMAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8428337 | 0.74 | TP53 (0.47) | MAPTALDH1A1CYP2C9TSHRMAPK1 | |
| SCHEMBL8428396 | 0.72 | SLC6A3 (0.44) | MAPTALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL8426400 | 0.70 | TRPA1 (0.50) | MAPTALDH1A1KDM4EPOLBCYP2C9 | |
| SCHEMBL8426401 | 0.70 | TRPA1 (0.50) | MAPTALDH1A1KDM4EPOLBCYP2C9 | |
| SCHEMBL7592950 | 0.67 | TRPA1 (0.50) | MAPTALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL7592948 | 0.67 | TRPA1 (0.50) | MAPTALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL29671567 | 0.67 | TUBB4A (0.51) | CTHMAPTPOLBLMNAMEN1 | |
| SCHEMBL11812062 | 0.66 | CA1 (0.52) | MAPTALDH1A1KDM4ECYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939561-A | Process for the preparation of β-phenylisoserine and β-lactam and their analogues | RHONE-POULENCE RORER S.A. (FR) | 1999-08-17 | — | — | US | disclosed |