Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532998 | 0.88 | PTGER4 (0.42) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL8429296 | 0.81 | MAPT (0.36) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL8531196 | 0.81 | PTGER4 (0.43) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL8532986 | 0.73 | PTGER4 (0.42) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL8531716 | 0.70 | PTGER4 (0.40) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL7378811 | 0.68 | PTGER4 (0.48) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL8429187 | 0.66 | ITGB3 (0.37) | FFAR1FFAR4 | |
| SCHEMBL8428908 | 0.65 | ITGB3 (0.38) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL8432521 | 0.64 | ABCB11 (0.41) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8479912 | 0.64 | PTGER4 (0.70) | FFAR1FFAR4PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952381-A | SELECTIVELY INHIBITING OR ANTAGONIZING THE INTEGRINS; ANTITUMOR AGENTS, ANTIARTHRITIC AGENTS, VIRICIDES, MICROBIOCIDES; TREATING OSTEOPOROSIS, SKIN DISORDERS | G. D. SEARLE & CO. (US) | 1999-09-14 | — | — | US | disclosed |