Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | ITGAV | P06756 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532998 | 0.91 | PTGER4 (0.42) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL8531716 | 0.87 | PTGER4 (0.40) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL8429309 | 0.81 | FFAR1 (0.37) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL8532986 | 0.78 | PTGER4 (0.42) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL8432521 | 0.74 | ABCB11 (0.41) | PTGER4PTGER3PTGER1PTGER2SIRT1 | |
| SCHEMBL8428908 | 0.74 | ITGB3 (0.38) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL8428888 | 0.73 | CA1 (0.37) | PTGER4PTGER3PTGER1PTGER2ITGB3 | |
| SCHEMBL8432903 | 0.73 | ITGB3 (0.39) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL8429321 | 0.72 | ITGB3 (0.38) | PTGER4PTGER3PTGER1PTGER2FFAR1 | |
| SCHEMBL8501524 | 0.71 | PFKFB3 (0.47) | PTGER4PTGER3PTGER1PTGER2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |