Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429938 | 0.98 | HRH3 (0.32) | HRH3L3MBTL1TLR7 | |
| SCHEMBL8702181 | 0.79 | ALDH1A1 (0.32) | L3MBTL1MEN1KMT2A | |
| SCHEMBL8431381 | 0.78 | HRH3 (0.33) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL15364814 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL8431255 | 0.76 | PRKCA (0.31) | HRH3TDP1 | |
| SCHEMBL9038759 | 0.76 | L3MBTL1 (0.36) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL3305755 | 0.73 | HRH3 (0.39) | HRH3L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL8680858 | 0.72 | FAAH (0.39) | L3MBTL1MEN1KMT2ATDP1MAPT | |
| SCHEMBL3307533 | 0.71 | HRH3 (0.36) | HRH3L3MBTL1MAPTMAPK1NPSR1 | |
| SCHEMBL8683180 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958817-A1 | COMPOSITION CONTAINING DIARYLALKANE DERIVATIVE AS THE ACTIVE INGREDIENT FOR TREATING OR PREVENTING PANCREATITIS | SANKYO COMPANY LIMITED (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |