Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CRHR1 | P34998 | 18/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491412 | 0.73 | PIK3CG (0.48) | — | |
| SCHEMBL7706336 | 0.72 | LMNA (0.33) | LMNACYP1A2MAPK1 | |
| SCHEMBL7712320 | 0.72 | CRHR1 (0.34) | LMNACYP1A2MAPK1CRHR1 | |
| SCHEMBL10407901 | 0.70 | PIK3CG (0.34) | LMNA | |
| SCHEMBL9664890 | 0.70 | PIK3CG (0.34) | LMNA | |
| SCHEMBL9038706 | 0.70 | RAB9A (0.41) | LMNA | |
| SCHEMBL5241060 | 0.70 | PIK3CG (0.34) | LMNA | |
| SCHEMBL7712313 | 0.69 | HTT (0.35) | LMNACRHR1 | |
| SCHEMBL10911368 | 0.68 | CYP1A2 (0.55) | LMNACYP1A2MAPK1CRHR1 | |
| Trapidil SCHEMBL19438921 | 0.68 | MAPK1 (1.00) | LMNACYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| JP-56079674-A | — | — | None | — | — | JP | disclosed |
| JP-59029689-A | — | — | None | — | — | JP | disclosed |
| JP-58174384-A | — | — | None | — | — | JP | disclosed |
| EP-3165606-A1 | METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL DISEASES | Ophthotech Corporation (US) | 2017-05-10 | — | — | EP | disclosed |
| US-20120100136-A1 | METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL DISEASES | OPHTHOTECH CORPORATION (US) | 2012-04-26 | — | — | US | disclosed |
| EP-2432476-A1 | METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL DISEASES | Ophthotech Corporation (US) | 2012-03-28 | — | — | EP | disclosed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |
| EP-0568451-B1 | Thermoplastic polymer composition and medical devices made of the same | TERUMO CORP (JP) | 1999-08-04 | — | — | EP | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5417981-A | Polymer and protease inhibitor formed by melt kneading the mixture | TERUMO KABUSHIKI KAISHA (JP) | 1995-05-23 | — | — | US | disclosed |
| EP-0568451-A1 | Thermoplastic polymer composition and medical devices made of the same | TERUMO KABUSHIKI KAISHA (JP) | 1993-11-03 | — | — | EP | disclosed |
| EP-0302132-B1 | Process and device for the preparation of 5-methyl-7-diethyl amino-s-triazolo[1,5-a] pyrimidine | Deutsche Hydrierwerke GmbH Rodleben (DE) | 1991-04-03 | — | — | EP | disclosed |
| EP-0302132-A1 | Process and device for the preparation of 5-methyl-7-diethyl amino-s-triazolo[1,5-a] pyrimidine | Deutsche Hydrierwerke GmbH Rodleben (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0302132-A1 | Process and device for the preparation of 5-methyl-7-diethyl amino-s-triazolo[1,5-a] pyrimidine | Deutsche Hydrierwerke GmbH Rodleben (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0075029-B1 | AGENT FOR TREATING CHRONIC OBLITERATIVE LUNG DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |
| JP-S5929689-A | PURIFICATION OF 5-METHYL-7-DIETHYLAMINO-S-TRIAZOLO(1,5-A) PYRIMIDINE | MITSUI PETROCHEM IND LTD | 1984-02-16 | — | — | JP | disclosed |
| JP-S58174384-A | PURIFICATION METHOD OF 5-METHYL-7-DIETHYLAMINO-S-TRIAZOLO (1,5-A)PYRIMIDINE | MITSUI PETROCHEM IND LTD | 1983-10-13 | — | — | JP | disclosed |
| JP-S5679674-A | PREPARATION OF AMINO GROUP-CONTAINING PYRIMIDINE DERIVATIVE | MITSUI PETROCHEM IND LTD | 1981-06-30 | — | — | JP | disclosed |