Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843044 | 0.72 | LMNA (0.51) | LMNACYP1A2MAPK1 | |
| SCHEMBL7706332 | 0.68 | LMNA (0.58) | LMNACYP1A2MAPK1GSK3B | |
| SCHEMBL3127589 | 0.67 | NOS3 (0.30) | — | |
| SCHEMBL8765848 | 0.67 | — | — | |
| SCHEMBL7201305 | 0.63 | CRHR1 (0.43) | — | |
| SCHEMBL29642153 | 0.63 | GSK3B (0.44) | LMNACYP1A2MAPK1GBA1GSK3B | |
| SCHEMBL7966725 | 0.60 | L3MBTL1 (0.36) | MAPK1 | |
| SCHEMBL11001134 | 0.56 | KDM4E (0.36) | LMNACYP1A2MAPK1GBA1 | |
| SCHEMBL2254013 | 0.56 | NUDT1 (0.47) | LMNACYP1A2MAPK1 | |
| SCHEMBL14158421 | 0.55 | DYRK1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | claimed |
| US-6369065-B1 | CEREBROVASCULAR AND CARDIOVASCULAR DISORDERS | UCB S.A. (BE) | 2002-04-09 | — | — | US | disclosed |