Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429055 | 0.84 | TRPV4 (0.35) | KMT2ARXFP1KCNK9 | |
| SCHEMBL8428895 | 0.84 | TRPV4 (0.35) | KMT2ARXFP1KCNK9 | |
| SCHEMBL8431235 | 0.84 | RXFP1 (0.32) | KMT2ARXFP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8429290 | 0.81 | CA1 (0.33) | KMT2ARXFP1RAB9AKCNK9MEN1 | |
| SCHEMBL8431435 | 0.81 | CA1 (0.32) | KMT2ARXFP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8430969 | 0.80 | NR1H4 (0.33) | KMT2ANPC1RAB9ASMN1; SMN2KCNK9 | |
| SCHEMBL8430960 | 0.79 | MAPT (0.35) | KMT2ARXFP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8432441 | 0.79 | KMT2A (0.32) | KMT2ARXFP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8430880 | 0.79 | CA1 (0.37) | KMT2ARXFP1SMN1; SMN2MEN1 | |
| SCHEMBL8429159 | 0.77 | NR1H4 (0.32) | KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952381-A | SELECTIVELY INHIBITING OR ANTAGONIZING THE INTEGRINS; ANTITUMOR AGENTS, ANTIARTHRITIC AGENTS, VIRICIDES, MICROBIOCIDES; TREATING OSTEOPOROSIS, SKIN DISORDERS | G. D. SEARLE & CO. (US) | 1999-09-14 | — | — | US | claimed |