Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | RORA | P35398 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | RORB | Q92753 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426879 | 0.87 | PGR (0.36) | ALDH1A1HPGDPGRRORARORC | |
| SCHEMBL8430906 | 0.82 | LMNA (0.35) | ALDH1A1HPGDGAAPGRRORA | |
| SCHEMBL8427005 | 0.69 | PDE9A (0.36) | ALDH1A1HPGDGAAPGRRORA | |
| SCHEMBL8428896 | 0.65 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPSR1MAPT | |
| SCHEMBL8430942 | 0.64 | GAA (0.38) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL8426881 | 0.61 | MAPT (0.43) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL7213298 | 0.60 | SIRT2 (0.64) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL11241641 | 0.60 | ALDH1A1 (0.46) | ALDH1A1HPGDGAAPGRRORA | |
| SCHEMBL23400450 | 0.59 | KMT2A (0.48) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL11922814 | 0.59 | CNR2 (0.53) | ALDH1A1HPGDPGRRORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |