Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | RORB | Q92753 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RGS4 | P49798 | 3/20 | 0.33 |
| ▸ | RGS8 | P57771 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430906 | 0.88 | LMNA (0.35) | PDE9ARORARORCRORBPGR | |
| SCHEMBL8428964 | 0.83 | L3MBTL1 (0.38) | KDM4EMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL8426879 | 0.82 | PGR (0.36) | PDE9ARORARORCRORBPGR | |
| SCHEMBL8430941 | 0.69 | ALDH1A1 (0.38) | RORARORCRORBPGRKDM4E | |
| SCHEMBL11424517 | 0.67 | RORA (0.39) | RORARORCRORBPGRKDM4E | |
| SCHEMBL8427006 | 0.62 | MAPT (0.41) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12752179 | 0.62 | KMT2A (0.41) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL838929 | 0.58 | RGS4 (0.58) | RORARORCRORBPGRPDE4A | |
| SCHEMBL8777494 | 0.58 | TDP1 (0.68) | RORARORCRORBPGRPDE4A | |
| SCHEMBL10533316 | 0.57 | ALDH1A1 (0.49) | RORARORCRORBPGRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889013-A | REACTING AN URACIL COMPOUND WITH N, O-BIS/TRIMETHYLSILYL/ACETAMIDE FOLLOWED BY TETRABUTYLAMMONIUM IODIDE AND CHLOROMETHYL ETHER COMPOUND AND THEN REACTING WITH ARYL SELENOL IN A BASE | SUNKYONG INDUSTRIES CO., INC. (KR) | 1999-03-30 | — | — | US | disclosed |