Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377093 | 0.83 | SLC6A5 (0.37) | HTR1AADRA1DADRA1AADRA1BTAS1R3 | |
| SCHEMBL8636164 | 0.82 | LMNA (0.39) | HTR1AADRA1DADRA1AADRA1BTAS1R3 | |
| SCHEMBL8679133 | 0.79 | ALDH1A1 (0.34) | HTR1AADRA1DADRA1AADRA1BNPSR1 | |
| SCHEMBL8378989 | 0.75 | ALDH1A1 (0.36) | HTR1AADRA1DADRA1AADRA1BTAS1R3 | |
| SCHEMBL8380383 | 0.75 | HTR1A (0.35) | HTR1AADRA1DADRA1AADRA1BTAS1R3 | |
| SCHEMBL8378913 | 0.75 | ALDH1A1 (0.39) | HTR1AADRA1DADRA1AADRA1BTAS1R3 | |
| SCHEMBL8636168 | 0.74 | L3MBTL1 (0.47) | HTR1AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL8378914 | 0.73 | HTR1A (0.39) | HTR1AADRA1DADRA1AADRA1BTAS1R3 | |
| SCHEMBL8380298 | 0.73 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1BTAS1R3 | |
| SCHEMBL8381714 | 0.73 | LMNA (0.39) | HTR1AADRA1DADRA1AADRA1BTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936083-A | BACTERICIDES | Uclaf, Roussel (FR) | 1999-08-10 | — | — | US | disclosed |