Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434720 | 0.78 | USP2 (0.44) | ALDH1A1TDP1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL7900079 | 0.74 | CYP2C19 (0.53) | ALDH1A1TDP1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL8432572 | 0.73 | PAM (0.42) | PAMTDP1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL7900060 | 0.71 | ALDH1A1 (0.66) | ALDH1A1PAMTDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8745101 | 0.69 | CYP2C19 (0.36) | ALDH1A1PAM | |
| SCHEMBL7900084 | 0.68 | MAOA (0.42) | ALDH1A1TDP1MAPT | |
| SCHEMBL10063779 | 0.68 | HPGD (0.51) | PAML3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL3194897 | 0.68 | TDP1 (0.54) | ALDH1A1TDP1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL7892776 | 0.67 | CYP1A2 (0.47) | ALDH1A1 | |
| SCHEMBL6416798 | 0.66 | ALDH1A1 (0.61) | ALDH1A1PAMTDP1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |