Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 3/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10990326 | 0.74 | PAM (0.55) | PAMTBXA2RPPARALMNANPC1 | |
| SCHEMBL8432568 | 0.73 | ALDH1A1 (0.36) | PAMLMNANPC1RAB9ATDP1 | |
| SCHEMBL8745101 | 0.71 | CYP2C19 (0.36) | PAMHPGDHTTKMT2A | |
| SCHEMBL10510400 | 0.71 | PAM (0.58) | PAMLMNAMAOBMMP1MMP2 | |
| SCHEMBL9857863 | 0.71 | PAM (0.58) | PAMLMNAMAOBMMP1MMP2 | |
| SCHEMBL9857754 | 0.68 | TDP1 (0.49) | PPARATDP1L3MBTL1KMT2A | |
| SCHEMBL5710793 | 0.67 | AKR1B10 (0.67) | AKR1B10AKR1B1LMNARAB9ATDP1 | |
| SCHEMBL9857547 | 0.67 | TSHR (0.47) | NAAALMNATDP1 | |
| SCHEMBL15929682 | 0.66 | AKR1B10 (0.65) | AKR1B10AKR1B1LMNARAB9ATDP1 | |
| SCHEMBL19800778 | 0.66 | GRIK1 (0.54) | PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |