Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434069 | 0.81 | LMNA (0.50) | ALDH1A1HPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL8432568 | 0.78 | ALDH1A1 (0.36) | NPC1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL7900079 | 0.73 | CYP2C19 (0.53) | USP2ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL8434924 | 0.71 | LMNA (0.40) | NPC1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL7900060 | 0.70 | ALDH1A1 (0.66) | ALDH1A1HPGDSMN1; SMN2MAPTTDP1 | |
| SCHEMBL11359120 | 0.70 | ESR1 (0.56) | ALDH1A1HPGDSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8745142 | 0.70 | ALDH1A1 (0.48) | USP2ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL7900084 | 0.67 | MAOA (0.42) | USP2ALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL7734314 | 0.67 | HPGD (0.55) | USP2NPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3194897 | 0.67 | TDP1 (0.54) | NPC1ALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |