SCHEMBL8433401

SCHEMBL8433401

C(Cc1ccccc1)=C(c1nccs1)c1nccs1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 1/20 0.49
CES1 P23141 1/20 0.48
TBXAS1 P24557 1/20 0.42
PDPK1 O15530 1/20 0.42
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RBBP9 O75884 1/20 0.38
MAOB P27338 1/20 0.36
CACNA2D1 P54289 1/20 0.35
SCN3A Q9NY46 2/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP7 P09237 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6142534 0.72 RBBP9 (0.46) PLA2G4ACES1TBXAS1PDPK1LMNA
SCHEMBL6142531 0.72 RBBP9 (0.46) PLA2G4ACES1TBXAS1PDPK1LMNA
SCHEMBL165353 0.71 PLA2G4A (0.66) PLA2G4ACES1PDPK1USP2LMNA
SCHEMBL6657643 0.70 PDPK1 (0.46) PLA2G4ACES1PDPK1USP2LMNA
SCHEMBL20196298 0.70 PLA2G4A (0.49) PLA2G4ACES1PDPK1USP2LMNA
SCHEMBL9346822 0.70 PLA2G4A (0.49) PLA2G4ACES1TBXAS1PDPK1USP2
SCHEMBL14288477 0.70 TBXAS1 (0.57) PLA2G4ACES1TBXAS1RBBP9
SCHEMBL6154147 0.69 RBBP9 (0.49) PLA2G4ACES1TBXAS1PDPK1LMNA
SCHEMBL6570545 0.68 PLA2G4A (0.47) PLA2G4ACES1PDPK1USP2LMNA
SCHEMBL22393879 0.68 PLA2G4A (0.54) PLA2G4ACES1LMNATSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5959070-A ELECTROOPTICS, LIGHT EMITTING DIODES; POLYBENZOXAZOLES, POLYBENZOTHIAZOLES, POLYBENZIMIDAZOLES UNIVERSITY OF ROCHESTER (US) 1999-09-28 US disclosed
US-5814833-A OPTICAL AND ELECTRONIC POLYMERS FOR ELECTRONICS, PHOTONICS AND OPTOELECTRONICS APPLICATIONS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-09-29 US disclosed
US-5726282-A Light emitting diode RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-03-10 US disclosed
US-5599899-A POLYBENZIMIDAZOLES, POLYBENZOTHIAZOLES OR POLYBENZOXAZOLES HOMO- OR COPOLYMERS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-02-04 US disclosed
US-5597890-A ENHANCED LUMINESCENCE AND PHOTOGENERATION OF CHARGE CARRIERS AND QUANTUM EFFICIENCY USING N-HETEROCYCLE AROMATIC RESINS AND AN ELECTRON DONOR OR ACCEPTOR; OPTOELECTRONICS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-01-28 US disclosed
WO-1995012628-A1 CONJUGATED POLYMER EXCIPLEXES AND APPLICATIONS THEREOF RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-05-11 WO disclosed