Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435101 | 0.92 | VCAM1 (0.50) | VCAM1ERN1KMT2AHPGDPOLB | |
| SCHEMBL8070684 | 0.88 | LMNA (0.49) | ERN1KMT2AMEN1SRD5A2LMNA | |
| SCHEMBL8070686 | 0.88 | LMNA (0.49) | ERN1KMT2AMEN1SRD5A2LMNA | |
| SCHEMBL8695884 | 0.87 | LMNA (0.39) | KMT2AHPGDPOLBCRHBPCRHR2 | |
| SCHEMBL8078533 | 0.79 | SRD5A2 (0.51) | ERN1KMT2AMEN1SRD5A2LMNA | |
| SCHEMBL14533387 | 0.77 | VCAM1 (0.50) | VCAM1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL8437445 | 0.75 | SRD5A2 (0.47) | ERN1KMT2AMEN1SRD5A2LMNA | |
| SCHEMBL8437651 | 0.73 | SRD5A2 (0.46) | HPGDCA12CA1CA2CA9 | |
| SCHEMBL5434766 | 0.72 | CA1 (0.53) | KMT2AHPGDCA12CA1CA2 | |
| SCHEMBL1067197 | 0.72 | ERN1 (0.56) | VCAM1ERN1KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |
| US-5827887-A | 5-ALPHA REDUCTASE INHIBITORS | ROUSSEL UCLAF (FR) | 1998-10-27 | — | — | US | disclosed |