Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433598 | 0.92 | VCAM1 (0.46) | VCAM1ERN1KMT2APOLBHPGD | |
| SCHEMBL8078533 | 0.86 | SRD5A2 (0.51) | ERN1KMT2ASRD5A2MEN1LMNA | |
| SCHEMBL14533387 | 0.81 | VCAM1 (0.50) | VCAM1KMT2AHPGDALDH1A1NPSR1 | |
| SCHEMBL8437445 | 0.80 | SRD5A2 (0.47) | ERN1KMT2ASRD5A2MEN1LMNA | |
| SCHEMBL8070686 | 0.79 | LMNA (0.49) | ERN1KMT2ASRD5A2MEN1LMNA | |
| SCHEMBL8070684 | 0.79 | LMNA (0.49) | ERN1KMT2ASRD5A2MEN1LMNA | |
| SCHEMBL8695884 | 0.78 | LMNA (0.39) | KMT2APOLBHPGDNPSR1SRD5A2 | |
| SCHEMBL5434766 | 0.77 | CA1 (0.53) | KMT2AHPGDALDH1A1NPSR1CA12 | |
| SCHEMBL29708208 | 0.73 | VCAM1 (0.59) | VCAM1ERN1KMT2APOLBHPGD | |
| SCHEMBL28534503 | 0.73 | TSHR (0.62) | KMT2APOLBHPGDALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |
| US-5827887-A | 5-ALPHA REDUCTASE INHIBITORS | ROUSSEL UCLAF (FR) | 1998-10-27 | — | — | US | disclosed |