Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078533 | 0.93 | SRD5A2 (0.51) | SRD5A2HCAR3TSHRCASP6LMNA | |
| SCHEMBL8070684 | 0.87 | LMNA (0.49) | SRD5A2HCAR3TSHRCASP6LMNA | |
| SCHEMBL8070686 | 0.87 | LMNA (0.49) | SRD5A2HCAR3TSHRCASP6LMNA | |
| SCHEMBL8433883 | 0.86 | SRD5A2 (0.47) | SRD5A2LMNA | |
| SCHEMBL8435101 | 0.80 | VCAM1 (0.50) | SRD5A2LMNAMEN1KMT2AERN1 | |
| SCHEMBL8695884 | 0.77 | LMNA (0.39) | SRD5A2HCAR3TSHRLMNAPARP1 | |
| SCHEMBL8435617 | 0.77 | SRD5A2 (0.46) | SRD5A2LMNA | |
| SCHEMBL8433598 | 0.75 | VCAM1 (0.46) | SRD5A2LMNAMEN1KMT2AERN1 | |
| SCHEMBL8437651 | 0.74 | SRD5A2 (0.46) | SRD5A2LMNA | |
| SCHEMBL8433248 | 0.73 | SRD5A2 (0.59) | SRD5A2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |