Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 6/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431463 | 0.89 | CNR2 (0.39) | SMPD1CNR2HDAC3HDAC1HDAC2 | |
| SCHEMBL8436422 | 0.81 | S1PR2 (0.31) | — | |
| SCHEMBL8436423 | 0.81 | S1PR2 (0.31) | — | |
| SCHEMBL9511501 | 0.79 | L3MBTL1 (0.40) | SMPD1CNR2HDAC3HDAC1HDAC2 | |
| SCHEMBL8435577 | 0.77 | L3MBTL1 (0.39) | SMPD1CNR2THRA | |
| SCHEMBL8434091 | 0.77 | L3MBTL1 (0.37) | CNR2HDAC1HDAC2 | |
| SCHEMBL8435107 | 0.76 | TLR4 (0.36) | CNR2HDAC1HDAC2 | |
| SCHEMBL10209192 | 0.74 | ALDH1A1 (0.40) | THRBLGALS3CA1CA2CA9 | |
| SCHEMBL10419023 | 0.72 | CA1 (0.47) | SMPD1CNR2LGALS3CA1CA2 | |
| SCHEMBL10419025 | 0.72 | CA1 (0.47) | SMPD1CNR2LGALS3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0288888-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |