Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433303 | 1.00 | MEN1 (0.39) | MEN1KMT2AHTTLMNARECQL | |
| SCHEMBL8716946 | 0.87 | ADRB2 (0.41) | HTTLMNANR3C1SMN1; SMN2STAT3 | |
| SCHEMBL8713922 | 0.87 | LMNA (0.49) | MEN1KMT2AHTTLMNARECQL | |
| SCHEMBL8713860 | 0.87 | HTT (0.47) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL8715550 | 0.86 | SMN1; SMN2 (0.47) | HTTLMNANPSR1MAPTSMN1; SMN2 | |
| SCHEMBL8716720 | 0.86 | CASR (0.49) | KMT2AHTTLMNAMAPTSMN1; SMN2 | |
| SCHEMBL8713335 | 0.85 | TAAR1 (0.44) | MEN1KMT2AHTTLMNANPSR1 | |
| SCHEMBL8718432 | 0.85 | LMNA (0.40) | MEN1KMT2AHTTLMNARECQL | |
| SCHEMBL8713244 | 0.84 | MEN1 (0.38) | MEN1KMT2AHTTLMNARECQL | |
| SCHEMBL8720152 | 0.83 | MEN1 (0.39) | MEN1KMT2ALMNANPSR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5902900-A | OPTICAL PURITY, USE AS ANTI-OBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| US-5679557-A | Process of asymmetrically reducing 1-phenyl-2-oxo-propane derivatives with microorganisms | DAICEL CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-10-21 | — | — | US | disclosed |