Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717242 | 0.89 | ESR1 (0.46) | LMNANPSR1ALDH1A1STAT3CYP3A4 | |
| SCHEMBL8714103 | 0.89 | EPHX2 (0.41) | LMNAALDH1A1STAT3CYP19A1CA2 | |
| SCHEMBL8718432 | 0.88 | LMNA (0.40) | LMNAKMT2AMEN1HTTRECQL | |
| SCHEMBL8712989 | 0.88 | MMP1 (0.43) | LMNAKMT2ASTAT3CYP19A1CA2 | |
| SCHEMBL8713860 | 0.88 | HTT (0.47) | LMNAKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL8433303 | 0.87 | MEN1 (0.39) | LMNAKMT2AMEN1HTTRECQL | |
| SCHEMBL8433905 | 0.87 | MEN1 (0.39) | LMNAKMT2AMEN1HTTRECQL | |
| SCHEMBL8719246 | 0.81 | ATM (0.40) | KMT2AHTTALDH1A1STAT3CYP19A1 | |
| SCHEMBL8716946 | 0.81 | ADRB2 (0.41) | LMNAHTTSTAT3CYP19A1CA2 | |
| SCHEMBL8715550 | 0.80 | SMN1; SMN2 (0.47) | LMNAHTTNPSR1ALDH1A1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |