Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713860 | 0.88 | HTT (0.47) | ADRB2SMN1; SMN2LMNACA2HTT | |
| SCHEMBL8715550 | 0.87 | SMN1; SMN2 (0.47) | HTR2BSMN1; SMN2LMNAHTTSTAT3 | |
| SCHEMBL8433905 | 0.87 | MEN1 (0.39) | SMN1; SMN2LMNACA2HTTSTAT3 | |
| SCHEMBL8433303 | 0.87 | MEN1 (0.39) | SMN1; SMN2LMNACA2HTTSTAT3 | |
| SCHEMBL8714103 | 0.87 | EPHX2 (0.41) | ADRB2ADRB1ABL1RIN1SMN1; SMN2 | |
| SCHEMBL8717145 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNA | |
| SCHEMBL8717242 | 0.82 | ESR1 (0.46) | ADRB2ADRB1SLC6A4SLC6A3LMNA | |
| SCHEMBL8718432 | 0.81 | LMNA (0.40) | KCNH2SMN1; SMN2LMNACA2HTT | |
| SCHEMBL8713922 | 0.81 | LMNA (0.49) | LMNACA2HTTSTAT3CYP19A1 | |
| SCHEMBL8712989 | 0.81 | MMP1 (0.43) | SMN1; SMN2LMNACA2STAT3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |