Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712989 | 0.90 | MMP1 (0.43) | SMN1; SMN2LMNAKDM4ECTSDSTAT3 | |
| SCHEMBL8716946 | 0.87 | ADRB2 (0.41) | SMN1; SMN2LMNAKDM4EHTR2BHTT | |
| SCHEMBL8713860 | 0.87 | HTT (0.47) | SMN1; SMN2LMNAKDM4EALDH1A1HTT | |
| SCHEMBL8433303 | 0.86 | MEN1 (0.39) | SMN1; SMN2LMNAMAPTCTSDNPSR1 | |
| SCHEMBL8433905 | 0.86 | MEN1 (0.39) | SMN1; SMN2LMNAMAPTCTSDNPSR1 | |
| SCHEMBL8713256 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAKDM4EMAPTTDP1 | |
| SCHEMBL8719228 | 0.83 | MAPT (0.44) | SMN1; SMN2LMNAKDM4EMAPTTDP1 | |
| SCHEMBL8717242 | 0.81 | ESR1 (0.46) | LMNAKDM4ENPSR1ALDH1A1STAT3 | |
| SCHEMBL8714103 | 0.81 | EPHX2 (0.41) | SMN1; SMN2LMNAKDM4ECTSDALDH1A1 | |
| SCHEMBL8718432 | 0.81 | LMNA (0.40) | SMN1; SMN2LMNAKDM4EMAPTCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |