⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL5863483 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL51408 | 0.72 | — | — | |
| SCHEMBL19881601 | 0.72 | — | — | |
| SCHEMBL8172271 | 0.70 | PTGS2 (0.33) | — | |
| Water SCHEMBL15210122 | 0.70 | ALDH1A1 (0.41) | — | |
| SCHEMBL160461 | 0.70 | — | — | |
| SCHEMBL4000711 | 0.70 | — | — | |
| SCHEMBL1990484 | 0.70 | — | — | |
| SCHEMBL1023100 | 0.70 | — | — | |
| Water SCHEMBL3454746 | 0.70 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382996-B | Specific inhibition plant plasma membrane H+-ATPase compound and preparation method and application thereof | 中国农业大学 | 2020-11-06 | — | — | CN | claimed |
| US-12583844-B2 | Matrix metalloproteinase (MMP) inhibitors and methods of use thereof | FORESEE PHARMACEUTICALS USA, INC. (US) | 2026-03-24 | — | — | US | disclosed |
| US-12503460-B2 | Matrix metalloproteinase (MMP) inhibitors and methods of use thereof | FORESEE PHARMACEUTICALS USA, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| US-12398089-B2 | Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand | NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) | 2025-08-26 | — | — | US | disclosed |
| US-12258335-B1 | Matrix metalloproteinase (MMP) inhibitors and methods of use thereof | FORESEE PHARMACEUTICALS USA, INC. (US) | 2025-03-25 | — | — | US | disclosed |
| US-20250057957-A1 | SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2025-02-20 | — | — | US | disclosed |
| CN-119462623-A | Matrix Metalloproteinase (MMP) inhibitors and methods of use thereof | 逸达生物科技美国公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119371425-A | Nitrogen-containing heterocyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-01-28 | — | — | CN | disclosed |
| EP-4058437-B9 | MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF USE THEREOF | FORESEE PHARMACEUTICALS USA INC (US) | 2025-01-15 | — | — | EP | disclosed |
| EP-4483875-A2 | SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Therapeutics, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-1995019774-A1 | BICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1995-07-27 | — | — | WO | disclosed |
| WO-1994017796-A1 | THERAPEUTIC USE OF COMPOUNDS HAVING SELECTIVE AGONIST-LIKE ACTIVITY ON RXR RETINOID RECEPTORS | ALLERGAN, INC. (US) | 1994-08-18 | — | — | WO | disclosed |
| US-4732901-A | BRONCHODILATORS | BEECHAM GROUP P.L.C. (GB) | 1988-03-22 | — | — | US | disclosed |
| US-4695634-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1987-09-22 | — | — | US | disclosed |
| US-4622406-A | CHEMICAL INTERMEDIATES, TRIMETHYLSILOXY COMPOUNDS | PFIZER INC. (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0194093-A2 | Substituted heterocyclic acrylic acids and esters, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1986-09-10 | — | — | EP | disclosed |
| US-4562267-A | Intermediates of hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1985-12-31 | — | — | US | disclosed |
| US-4423233-A | ALPHA-HYDROXY CARBOXIMIDATE INTERMEDIATES | PFIZER INC. (US) | 1983-12-27 | — | — | US | disclosed |
| US-4381308-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-04-26 | — | — | US | disclosed |
| US-4332952-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1982-06-01 | — | — | US | disclosed |