Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843402 | 0.77 | — | — | |
| Furfural SCHEMBL2201570 | 0.73 | ALDH1A1 (0.56) | LMNA | |
| Ethylene SCHEMBL9871986 | 0.73 | LMNA (0.38) | LMNA | |
| Ethylene SCHEMBL6226363 | 0.72 | LMNA (0.48) | LMNA | |
| SCHEMBL633362 | 0.72 | ALDH1A1 (0.32) | — | |
| Ethylene SCHEMBL8532842 | 0.72 | LMNA (0.41) | LMNA | |
| Ethylene SCHEMBL5863228 | 0.71 | LMNA (0.35) | LMNA | |
| SCHEMBL3905460 | 0.69 | LMNA (0.40) | LMNA | |
| Furfural SCHEMBL4869864 | 0.69 | ALDH1A1 (0.60) | LMNA | |
| Ethylene Glycol SCHEMBL5734322 | 0.69 | LMNA (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087590-B2 | 19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-08-08 | — | — | US | disclosed |
| US-20030162701-A1 | 19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162701-A1 | 19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them | ATP6V1B2, ATP6V1B1, ATP1A2 | LMNA 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.