Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434720 | 0.81 | USP2 (0.44) | LMNAHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7900079 | 0.80 | CYP2C19 (0.53) | LMNAALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL3383369 | 0.73 | HDAC3 (0.57) | LMNAALDH1A1SMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL8434078 | 0.73 | HDAC3 (0.52) | LMNATSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8434074 | 0.73 | ALDH1A1 (0.49) | LMNATSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8434924 | 0.72 | LMNA (0.40) | LMNATSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7900060 | 0.71 | ALDH1A1 (0.66) | TSHRHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10081169 | 0.70 | TSHR (0.60) | LMNATSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8745112 | 0.70 | HPGD (0.51) | LMNATSHRHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL3386410 | 0.69 | HDAC1 (0.62) | LMNATSHRALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |