Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434927 | 0.82 | ALDH1A1 (0.45) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL10990326 | 0.80 | PAM (0.55) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL9840562 | 0.76 | HDAC1 (0.76) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL9840567 | 0.76 | HDAC1 (0.76) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL8434069 | 0.73 | LMNA (0.50) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL8745112 | 0.72 | HPGD (0.51) | LMNATSHRALDH1A1HPGDGAA | |
| (Z)-1,2-Diphenylethene SCHEMBL27882891 | 0.72 | PPARA (0.66) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| (Z)-1,2-Diphenylethene SCHEMBL27882892 | 0.72 | PPARA (0.66) | HDAC3HDAC4HDAC1HDAC2HDAC10 | |
| SCHEMBL8434074 | 0.72 | ALDH1A1 (0.49) | LMNATSHRALDH1A1HPGDMEN1 | |
| SCHEMBL9396046 | 0.70 | HDAC1 (0.49) | HDAC1HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |