Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434078 | 0.82 | HDAC3 (0.52) | ALDH1A1HPGDPAMKMT2AMEN1 | |
| SCHEMBL10990326 | 0.80 | PAM (0.55) | ALDH1A1HPGDPAMKMT2ALMNA | |
| (Z)-1,2-Diphenylethene SCHEMBL27527844 | 0.68 | ALDH1A1 (0.73) | ALDH1A1PAMKMT2ALMNARAB9A | |
| SCHEMBL19800782 | 0.66 | GRIK1 (0.54) | PAM | |
| SCHEMBL19800778 | 0.66 | GRIK1 (0.54) | PAM | |
| SCHEMBL7433097 | 0.65 | S1PR1 (0.64) | ALDH1A1PAMKMT2ARAB9AHDAC3 | |
| SCHEMBL7427930 | 0.65 | S1PR1 (0.64) | ALDH1A1PAMKMT2ARAB9AHDAC3 | |
| SCHEMBL666894 | 0.65 | PAM (0.64) | ALDH1A1PAMLMNAHDAC3HDAC4 | |
| SCHEMBL1232837 | 0.65 | PAM (0.64) | ALDH1A1PAMLMNAHDAC3HDAC4 | |
| SCHEMBL1231739 | 0.65 | PAM (0.64) | ALDH1A1PAMLMNAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888723-A | SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |