Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8438684 | 0.90 | PDK1 (0.39) | PDK1PDK2PDK3PDK4MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL8439075 | 0.86 | PREP (0.37) | PDK1PDK2PDK3PDK4PREP | |
| Trifluoromethanesulfonic Acid SCHEMBL8435836 | 0.81 | CCR5 (0.36) | PDK1PDK2PDK3PDK4MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL8434762 | 0.81 | CCR5 (0.35) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL9127885 | 0.78 | PDK1 (0.39) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL8438343 | 0.78 | PDK1 (0.38) | PDK1PDK2PDK3PDK4PREP | |
| Trifluoromethanesulfonic Acid SCHEMBL8541838 | 0.77 | PDK1 (0.35) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL8436337 | 0.76 | ALDH1A1 (0.36) | PDK1PDK2PDK3PDK4MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL9124700 | 0.76 | PDK1 (0.41) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL8574927 | 0.75 | CTSK (0.46) | MAPTALDH1A1LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |